Our mission
Scientific Discoveries
We are studying the fundamental scientific principles at the interfaces of biological and material systems.
Curiosity has the boundless power to drive scientific discoveries. We acquire inspiration from biophysics, material science and engineering, electronics and neurobiology and investigate the phenomena of magnetism, electricity, chemistry and optics between the material and nervous systems. These fundamental principles can further guide us to effective engineering designs for biomedical applications.
biotechnology advancement
We are developing effective engineering methodologies to investigate neurobiological questions.
Biotechnology advancement is an indispensable catalyst for addressing neurobiological questions. Targeting specific technological challenges in neurobiology, we synthesize and fabricate functional materials, from nanoscale materials to devices, and apply them as engineering tools with various modalities to study the neural mechanisms underlying neurological and psychiatric disorders, including depression, addiction and social deficits.
Research
We are working in multiple-disciplinary fields to promote biomedical engineering advancement
Integrated neural probes
Fiber-inspired devices for probing nervous system with optical, electrical and pharmacological approaches
Team
We are an energertic group with material scientitsts, electrical engineers, bioengineers and chemists.

Siyuan Rao
Assistant Professor
Eunji Hong
PhD Student
Xinxin Xu
PhD Student
Zuer Wu
PhD Student
Wenjie Long
PhD Student
Ruobai Xiao
Master Student
Chen Lin
Master Student
Ian Kim
Master Student
Christian Capitano
Undergrad StudentNews
04/2025 Siyuan Rao has been selected as the recipient of the 2024-25 Watson College Recognition Award for Early-Stage Distinguished Research. Congratulations!.
04/2025 Sizhe Huang has been selected as the recipient of the 2024 Distinguished Dissertation Award!This prestigious award recognizes exceptional research and scholarly contributions of doctoral students. Congratulations!.
03/2025 Together with Profs. Qianbin Wang (BME Department) and Wenfeng Zhao (ECE Department), NBI team is awarded with S.H. Ho Foundation Research Grants (HFRG) for Health Sciences and Technology.
03/2025 NBI lab presented in Binghamton University BME Expo. Congratulations to Christian Capitano on winning First Place Undergraduate Research Poster Award!
03/2025 Welcome Wenjie Long joining our group!
01/2025 Congratulations to Sizhe Huang on winning Binghamton Unviersity Graduate Student Award for Excellence in Research Award!
01/2025 Welcome Ian Kim and Christian Capitano joining our group!
01/2025 Congratulations to Sizhe Huang on publishing Anisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo on Nature Communications!
12/2024 Siyuan Rao won Scholar Travel Award from National Institute on Biomedical Imaging and Bioengineering (NIBIB).
11/2024 Congratulations to Sizhe Huang on his successful PhD defense!
11/2024 Siyuan Rao is named Rising Stars of Mechanical Engineering from American Society of Mechanical Engineers.
10/2024 Siyuan Rao won Young Investigator Award from World Association for Chinese Biomedical Engineers workshop in the Biomedical Engineering Society.
10/2024 Congratulations to Sizhe Huang and Ruobai Xiao on winning Travel Grant for Workshop on Neuromorphic Principles in Biomedicine and Healthcare.
09/2024 Our collaborative work Near-infrared activated liposomes for neuroprotection in glaucoma is published on J. Mater. Chem. B.
05/2024 Welcome Chen Lin and Sandra Lwin joining our group!
05/2024 Siyuan Rao has been named a Scholarly Teaching Fellow in recognition of demonstrated commitment to undergraduate education by participating in the 2024 Evidence-Based Teaching Institute.
03/2024 Congratulations to Sizhe Huang on publishing Control of Polymers’ Amorphous-crystalline Transition Enables Miniaturization and Multifunctional Integration for Hydrogel Bioelectronics on Nature Communications!
12/2023 Welcome Zuer Wu joining our group!
10/2023 Our hydrogel fiber optics Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion on Nature Methods!
09/2023 Welcome Dorcas Matuwana and Geunho Jang joining our group!
09/2023 We started our new exciting journey at Binghamton University!
06/2023 NBI lab received the OTCV award from UMass Present's Office to provide a better soft-materials solution for recording neural activity and administering drugs in mobile-nerve regions.
05/2023 Congratulations to Sizhe Huang on publishing A nanoscale inorganic coating strategy for stabilizing hydrogel neural probes in vivo on the Journal of Materials Chemistry B!
04/2023 Welcome Ruobai Xiao and Xinxin Xu joining our group! Ruobai and Xinxin are enrolled in MSE PhD program starting from 2023 Summer. Welcome Dr. Yong Zhuang joining us as a Research Fellow. Welcome undergraduate students, Sabrina Urbina Villafranca, Rachel Collins, Omri Yosfan, Nicolle Gudiel Winter, Amanda Kanashiro, joining our group
01/2023 NBI Lab received the National Science Foundation’s (NSF) Faculty Early Career Development (CAREER) Program.
12/2022 Congratulations to Eunji Hong and Christopher Glynn on publishing Non-Invasive Electroretinogram Recording with Simultaneous Optogenetics to Dissect Retinal Ganglion Cells Electrophysiological Dynamics on Biosensors!
12/2022 NBI Lab received 2023 AFOSR Young Investigator Program Award.
6/2022 NBI Lab received UMass FRG 2022 award.
6/2022 Welcome undergraduate students Ifeoluwa Adeniyi, Rachel Collins, joining our group! Welcome REU student, Noah Flores, and high-school students, Trevor Xing-Xie, Ava Zimmermann, Kaitlin Aquilino working with us! high-school students Ifeoluwa Adeniyi, Rachel Collins, joining our group!
5/2022 Congratulations to Eunji Hong and Weixuan Chen on passing their Qualifying exams!
5/2022 Congratulations to Dr. Qianbin Wang on publishing his experimental Glaucoma mouse model, Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion Cells, on Neuron!
4/2022 Congratulations to Weixuan Chen on her IONs Inspirations Award! Congratulations to Collin Maley on winning Distinguished Biomedical Engineering Fellowship with the admission to Boston University PhD program!
1/2022 Welcome undergraduate students Sarah Shams, Jingyi (Alex) Xu, Christopher Glynn, Arzell Jelani Steans and Varun Gopal joining our group!
11/2021 Dr. Siyuan Rao, Dr. Qianbin Wang, Sizhe Huang, Collin Maley, Jacob Naroian attended UMass Interdisciplinary Neuroscience, Computer Science & Engineering Poster Conference. Collin Maley won Third Place Award. Well done, everyone!
10/2021 Welcome Dr. Jia Xu visiting NBI lab!
10/2021 Dr. Siyuan Rao received the Young Investigator Grant from Brain& Behavior Research Foundation (BBRF). Thanks for the funding support!
08/2021 Welcome BME undergraduate students Jacob Tajchman, Sophia Tsekov, Trisha Raman and Aaryan Chaudhary joining our group!
08/2021 Welcome Eunji Hong and Weixuan Chen joining our group! Eunji and Weixuan are enrolled in BME PhD program starting from 2021 Fall.
07/2021 Congratulations to Sizhe Huang on passing his Qualify Exam of BME PhD program!
07/2021 Kayla Felix, Collin Maley and Jacob Naroian are awarded with Honors Research Grants for their undgergraduate research projects! Congratulations!
05/15/2021 Congratulations to Christine Yao (Class of BME 2021) on her graduation!
03/29/2021 Dr. Siyuan Rao and Jingyi Qiu expressed their Viewpoint about Material Engineering Platform for Next Generation of Neurobiological Interfaces on Accounts of Materials Research.
03/13/2021 NBI team first campus tour retreat. After COVID-19 lockdown over one full year, we cherish the moment of unity during the challenging pandemic time.
02/02/2021 Dr. Siyuan Rao joined UMass Neuroscience and Behavior (NSB) program as a core faculty member. NSB PhD students are welcomed to find research opportunities in our lab.
01/2021 Collin Maley, Jacob Naroian and Sizhe Huang joined our lab. We are excited to have fresh blood to strengthen our team. Welcome!
01/12/2021 Kayla Felix was selected as Junior Fellow into Junior Fellowship Program at UMass. Congratulations to Kayla!
12/01/2020 NBI Lab opened for bussiness.
2020 Fall semester Jingyi Qiu, Kayla Felix and Christine Yao joined NBI Lab. We are so pround to have these young women scientists as the first generation of lab members in our team. Welcome!
Contact
BI 2213, 85 Murray Hill Rd
Vestal, NY 13902
syrao@binghamton.edu
+1 607 777 5784